Endoplasmic Reticulum-Associated Degradation Factor ERLIN2 : Oncogenic Roles and Molecular Targeting of Breast Cancer
نویسندگان
چکیده
s: “Endoplasmic reticulum factor ERLIN2 plays an oncogenic role by modulating ER stress response in breast cancer” DOD BCRP Era of Hope Meeting 2011 “Endoplasmic Reticulum Factor ERLIN2 Preserves Oncogenesis by Regulating De novo Lipogenesis” DOD BCRP Era of Hope Meeting 2011
منابع مشابه
Endoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cells.
Increased de novo lipogenesis is a hallmark of aggressive cancers. Lipid droplets, the major form of cytosolic lipid storage, have been implicated in cancer cell proliferation and tumorigenesis. Recently, we identified the ERLIN2 [ER (endoplasmic reticulum) lipid raft-associated 2) gene that is amplified and overexpressed in aggressive human breast cancer. Previous studies demonstrated that ERL...
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